name ABCB1 I1145I ABCB1 Overexpression ABCB1 S893A/T ABCB1 S893T ABCC10 Overexpression ABCC3 Amplification ABCG2 Q141K ABL1 C475V ABL1 Double Ph ABL1 G340L ABL1 L298V ABL1 Non-P-Loop Mutation ABL1 P-Loop Mutation ABL1 R351W ABL1 TKD Mutation ABL1 V379I ABL2 W469C ACTA1 EXPRESSION ACTB::GLI1 Fusion ACVR1 G328E ACVR1 G328V ACVR1 G328W ACVR1 G356D ACVR1 Gain-of-Function ACVR1 Mutation ACVR1 R206H AFAP1::NTRK2 Fusion AGGF1::PDGFRB Fusion AND PDGFRB C843G AGK::BRAF Fusion AGR2 EXPRESSION AKAP9::BRAF Fusion AKT1 E17K AKT1 Overexpression AKT1 Q79K AKT1 S473 Phosphorylation AKT2 Amplification AKT2 EXPRESSION AKT3 E17K AKT3 Overexpression ALCAM EXPRESSION ALDH1A2 Overexpression ALDH1A2 Underexpression ALK Alternative Transcript (ATI) ALK Exon 4-11 Deletion ALK F1174L ALK F1245C ALK F1245V ALK G1202R AND v::ALK Fusion ALK G1269A AND v::ALK Fusion ALK I1171 ALK I1171N AND HIP1::ALK Fusion ALK I1171T ALK Mutation ALK R1275Q ANO10::RAF1 Fusion APC Mutation APP::NRG1 Fusion AR AR-V7 AR F877L AR Mutation AR OVEREXPRESSION AR R726L AR W742 ARAF S214C ARAF S214F ARAF V145L AREG Expression ARID1A Loss ARID1A Loss OR ARID1A Wildtype ARID1A P1175FS*5 ARID1A Q456* ARID1A Underexpression ASNS Amplification ASPSCR1::TFE3 Fusion ASS1 Loss ASXL1 EXON 12 MUTATION ASXL1 Mutation ATF7IP::JAK2 Fusion ATM A2062V ATM c.7089+1del ATM c.7515+1_2del ATM c.902-1G>T ATM C2488Y ATM D1682H ATM D1930V ATM E2187* ATM F1025L ATM F2732V ATM K293* ATM K468FS ATM L2427P ATM Mutation ATM N2875H ATM R3008C ATM S2289* ATM T2666A ATM Underexpression ATP1B1::NRG1 Fusion ATR I774FS ATRX Deletion ATRX Mutation ATRX Underexpression AURKA Amplification AURKA EXPRESSION AURKA Overexpression AXL EXPRESSION B2M S14FS B4GALT1 Overexpression BAP1 ALTERNATIVE TRANSCRIPT (ATI) BAP1 EXPRESSION BAP1 Mutation BARD1 Loss-of-function BARD1 Mutation BCL2 F104I BCL2 G101V BCL2 Mutation BCL2 Overexpression BCL2 reg_e@[IGH]::BCL2 BCL2L11 Deletion Polymorphism BCOR ITD BCOR Mutation BCOR::CCNB3 Fusion BCR::ABL1 Fusion BCR::ABL1 Fusion AND ABL1 A397P BCR::ABL1 Fusion AND ABL1 D276G BCR::ABL1 Fusion AND ABL1 D363G BCR::ABL1 Fusion AND ABL1 D421G BCR::ABL1 Fusion AND ABL1 E255K BCR::ABL1 Fusion AND ABL1 E255K AND ABL1 V299L BCR::ABL1 Fusion AND ABL1 E255V BCR::ABL1 Fusion AND ABL1 E279K BCR::ABL1 Fusion AND ABL1 E292L BCR::ABL1 Fusion AND ABL1 E292V BCR::ABL1 Fusion AND ABL1 E355G BCR::ABL1 Fusion AND ABL1 E450Q BCR::ABL1 Fusion AND ABL1 E450V BCR::ABL1 Fusion AND ABL1 E453A BCR::ABL1 Fusion AND ABL1 E453K BCR::ABL1 Fusion AND ABL1 E453Q BCR::ABL1 Fusion AND ABL1 E459K BCR::ABL1 Fusion AND ABL1 E98G BCR::ABL1 Fusion AND ABL1 F311I BCR::ABL1 Fusion AND ABL1 F311L BCR::ABL1 Fusion AND ABL1 F317C BCR::ABL1 Fusion AND ABL1 F317I BCR::ABL1 Fusion AND ABL1 F317L BCR::ABL1 Fusion AND ABL1 F317R BCR::ABL1 Fusion AND ABL1 F317S BCR::ABL1 Fusion AND ABL1 F317V BCR::ABL1 Fusion AND ABL1 F359C BCR::ABL1 Fusion AND ABL1 F359I BCR::ABL1 Fusion AND ABL1 F359V BCR::ABL1 Fusion AND ABL1 F486S BCR::ABL1 Fusion AND ABL1 G250E BCR::ABL1 Fusion AND ABL1 G398R BCR::ABL1 Fusion AND ABL1 H396P BCR::ABL1 Fusion AND ABL1 H396R BCR::ABL1 Fusion AND ABL1 L248R BCR::ABL1 Fusion AND ABL1 L248R AND ABL1 F359I BCR::ABL1 Fusion AND ABL1 L248V BCR::ABL1 Fusion AND ABL1 L364I BCR::ABL1 Fusion AND ABL1 L364I AND ABL1 M244V BCR::ABL1 Fusion AND ABL1 L364P BCR::ABL1 Fusion AND ABL1 L384M BCR::ABL1 Fusion AND ABL1 L387F BCR::ABL1 Fusion AND ABL1 L387M BCR::ABL1 Fusion AND ABL1 M244V BCR::ABL1 Fusion AND ABL1 M343T BCR::ABL1 Fusion AND ABL1 M351T BCR::ABL1 Fusion AND ABL1 M388L BCR::ABL1 Fusion AND ABL1 N146S BCR::ABL1 Fusion AND ABL1 N331S BCR::ABL1 Fusion AND ABL1 N336S BCR::ABL1 Fusion AND ABL1 P480A BCR::ABL1 Fusion AND ABL1 Q252H BCR::ABL1 Fusion AND ABL1 Q300R BCR::ABL1 Fusion AND ABL1 S417Y BCR::ABL1 Fusion AND ABL1 S438C BCR::ABL1 Fusion AND ABL1 T315A BCR::ABL1 Fusion AND ABL1 T315I BCR::ABL1 Fusion AND ABL1 T315V BCR::ABL1 Fusion AND ABL1 V289I BCR::ABL1 Fusion AND ABL1 V299L BCR::ABL1 Fusion AND ABL1 V379I BCR::ABL1 Fusion AND ABL1 Y253F BCR::ABL1 Fusion AND ABL1 Y253H BCR::JAK2 Fusion BCR::NTRK2 Fusion BCR::PDGFRA Fusion BIRC3 TRUNCATING MUTATION BIRC5 NUCLEAR EXPRESSION BIRC5 Overexpression BIRC7 Amplification BRAF A598V BRAF A728V BRAF Amplification BRAF Amplification AND ( BRAF V600E OR BRAF V600K ) BRAF D594A BRAF D594G BRAF D594K BRAF D594V BRAF DEL 485-490 BRAF Exon 15 Mutation BRAF G463E BRAF G464V BRAF G466V BRAF G469 BRAF G469A BRAF G469E BRAF G496A BRAF G596C BRAF G596R BRAF G606E BRAF intron 10 rearrangement BRAF intron 9 rearrangement BRAF K483M BRAF K601E BRAF L505H BRAF L597Q BRAF L597R BRAF L597S BRAF L597V BRAF Mutation BRAF N486_P490del BRAF N581S BRAF Non-V600 BRAF P731T BRAF V600 BRAF V600 AND BRAF Amplification BRAF V600 OR v::BRAF Fusion BRAF V600_K601>E BRAF V600D BRAF V600E BRAF V600E AND ARAF S490T BRAF V600E AND BRAF Amplification BRAF V600E AND BRAF V600M BRAF V600E AND EZH2 Y646F BRAF V600E AND GNAS R201C BRAF V600E AND NF1 Loss BRAF V600E OR BRAF K601E BRAF V600E OR KIAA1549::BRAF Fusion BRAF V600E OR NRAS Mutation OR HRAS Mutation OR KRAS Mutation OR NF1 Inactivating Mutation BRAF V600E OR NRAS Mutation OR HRAS Mutation OR KRAS Mutation OR NF1 Mutation BRAF V600K BRAF Wildtype BRAF::CUL1 Fusion BRCA1 Alu insertion BRCA1 Expression BRCA1 Loss-of-function BRCA1 Loss-of-function OR BAP1 Loss-of-function BRCA1 Mutation BRCA1 Mutation OR BRCA2 Mutation BRCA1 P968FS BRCA1 Q1467* BRCA1 Underexpression BRCA1 W1815X BRCA2 D3095E BRCA2 K3326* BRCA2 Loss-of-function BRCA2 M1I BRCA2 M1R BRCA2 Mutation BRCA2 R2336P BRCA2 TRUNCATING MUTATION BRCA2 V159M BRCA2 V211I BRCA2 V211L BRD4::NUTM1 Fusion BRIP1 Mutation BTK C481S BTK MUTATION BTK T316A C19MC Alterations C19MC Amplification C19MC TTYH1::C19MC fusion C19MC v::C19MC fusion CAD::ALK Fusion CALR EXON 9 FRAMESHIFT CALR Mutation CASP8 D302H CASP8 Overexpression CBFA2T3::GLIS2 Fusion CBFB::MYH11 Fusion CBL Y371H CBLB RS2305035 CBLC EXPRESSION CCDC6::RET Fusion CCND1 Amplification CCND1 Amplification OR CCND2 Amplification OR CCND3 Amplification CCND1 Expression CCND1 Overexpression CCND2 OVEREXPRESSION CCND2 PROMOTER DEMETHYLATION CCND3 Loss CCNE1 Amplification CCNE1 Overexpression CCNE1 Underexpression CD274 Expression CD44 CD44s Expression CD44 CD44v6 CD72::ROS1 Fusion CDH1 MUTATION CDK12 Loss-of-function CDK12 Mutation CDK4 Amplification CDK4 EXPRESSION CDK4 R24C CDK6 EXPRESSION CDK6 Overexpression CDKN1A EXPRESSION CDKN1A rs1059234 CDKN1A rs1801270 CDKN1B CYTOPLASMIC MISLOCALIZATION CDKN1B EXPRESSION CDKN2A c.151-1G>C CDKN2A Deletion CDKN2A Loss CDKN2A Loss OR CDKN2A Mutation CDKN2A Mutation CDKN2A p16 Expression CDKN2A Promoter Hypermethylation CDKN2A RS3814960 CDKN2B Loss CDKN2B METHYLATION CDX2 EXPRESSION CEBPA BIALLELIC INACTIVATION CEBPA Mutation CEBPA N-TERMINAL FRAME SHIFT CENPC::ABL1 Fusion CFLAR EXPRESSION CHD7::BEND2 Fusion CHEK1 Mutation CHEK1 Overexpression CHEK2 1100DELC CHEK2 I157T CHEK2 IVS2+1G>A CHEK2 Loss-of-function CHEK2 mutation CHEK2 R474C c.1420C>T CIC::DUX4 Fusion CIP2A EXPRESSION CIP2A Underexpression CK High CLTC::ALK Fusion COL1A1::PDGFB Fusion CRBN Mutation CSF3R Mutation CSF3R T618I CTAG1B Overexpression CTAG2 Overexpression CTCF K365T CTLA4::CD28 Fusion CTNNB1 Activating Mutation CTNNB1 Exon 3 Mutation CTNNB1 S45F CTNNB1 S45P CTNNB1 T41A CUX1::BRAF Fusion CXCR4 EXPRESSION CYP2D6 Loss-of-function DCC EXPRESSION DDR2 G253C DDR2 G505S DDR2 G774V DDR2 I638F DDR2 L239R DDR2 L63V DDR2 S768R DDR2::NTRK1 Fusion DDX41 R164W DDX43 Overexpression DEFA1 EXPRESSION DICER1 D1709E DICER1 D1709G DICER1 D1709N DICER1 E1705K DICER1 E1813Q DKK1 NUCLEAR EXPRESSION DNAJB1::PRKACA Fusion DNMT1 EXPRESSION DNMT3A Mutation DNMT3A R882 DPYD DPYD*13 HOMOZYGOSITY DPYD DPYD*2A HOMOZYGOSITY DPYD EXON 11-19 DELETION DPYD RS67376798 HOMOZYGOSITY DUSP6 EXPRESSION DUX4::v Fusion EBF1::JAK2 Fusion EBF1::PDGFRB Fusion ECSCR EXPRESSION EGF EXPRESSION EGFR A289V EGFR A763_Y764insFQEA EGFR A767_V769dupASV EGFR A864T EGFR Amplification EGFR Amplification AND EGFR EGFRVIII EGFR Amplification AND EGFR::SEPTIN14 Fusion EGFR C797S EGFR C797Y EGFR Copy Number Variation EGFR D761Y EGFR D770_N771insG EGFR D770_N771insGL EGFR D770_N771insGT EGFR D770_N771insNPG EGFR D770_N771insSVD EGFR D770delinsGY EGFR E114K EGFR E734Q EGFR E746_A750del EGFR E746_T751>I EGFR E746G EGFR E868G EGFR Exon 18 Overexpression EGFR Exon 19 Deletion EGFR Exon 20 Insertion EGFR Exon 4 Deletion EGFR Expression EGFR G465R EGFR G598V EGFR G719 EGFR G719A EGFR G719D EGFR G719S EGFR G724S EGFR Gain-of-function EGFR H773_V774insH EGFR H773_V774insNPH EGFR K467T EGFR K754E EGFR K757R EGFR K806E EGFR L747_P753delinsS EGFR L747_S752delinsQ EGFR L747P EGFR L838P EGFR L838V EGFR L858R EGFR L858R OR EGFR Exon 19 Deletion EGFR L861 EGFR L861Q EGFR L861R EGFR M766_A767insAI EGFR M766_A767insASV EGFR Mutation EGFR N771_P772insL EGFR N826S EGFR N826Y EGFR N842S EGFR Overexpression EGFR P753S EGFR P772_H773insYNP EGFR P772_V774insPHV EGFR R108K EGFR R222C EGFR R252C EGFR R451C EGFR R705K EGFR R776C EGFR R831H EGFR Rare Exon 18-21 Mutation EGFR Rare Mutation EGFR S492R EGFR S645C EGFR S720 EGFR S768_D770dup EGFR S768I EGFR S768I OR EGFR G719A OR EGFR L861Q EGFR T263P EGFR T785A EGFR T790M EGFR T790M AND EGFR Exon 19 Deletion EGFR T790M AND EGFR Exon 19 Deletion AND EGFR C797S EGFR T847I EGFR V441F EGFR V742A EGFR V769_D770insASV EGFR V774A EGFR V774M EGFR V834I EGFR V851I EGFR VIII EGFR W731L EGFR Wildtype EGFR Y1092 PHOSPHORYLATION EGFR Y764_V765insHH EGFR Y801H EGFR::PURB Fusion EGFR::RAD51 e24::e4 EGFR::RAD51 Fusion EGFR::USP42 Fusion EIF1AX MUTATION EIF4EBP1 PHOSPHORYLATION EML4::ALK e2::e20 EML4::ALK e20::e20 EML4::ALK e6::e20 EML4::ALK Fusion EML4::ALK Fusion AND ALK Amplification EML4::ALK Fusion AND ALK C1156Y EML4::ALK Fusion AND ALK F1245C EML4::ALK Fusion AND ALK G1202R EML4::ALK Fusion AND ALK G1202R AND ALK I1171N AND ALK L1196M EML4::ALK Fusion AND ALK G1269A EML4::ALK Fusion AND ALK I1171N AND ALK L1196M EML4::ALK Fusion AND ALK I1171S EML4::ALK Fusion AND ALK L1152R EML4::ALK Fusion AND ALK L1196M EML4::ALK Fusion AND ALK L1198F AND ALK C1156Y EML4::ALK Fusion AND ALK S1206Y EML4::ALK Fusion AND ALK T1151dup EML4::ALK Fusion AND ALK V1180L EML4::NTRK3 Fusion EPAS1 Overexpression EPCAM 3' Exon Deletion EPHB4 EXPRESSION EPOR rearrangements ERBB2 A775_G776insTVMA ERBB2 A775_G776insV ERBB2 A775_G776insVVMA ERBB2 Activating Mutation ERBB2 Amplification ERBB2 D769H ERBB2 D769Y ERBB2 Exon 20 Insertion ERBB2 G309A ERBB2 G776_V777delinsVCD ERBB2 G776delinsCV ERBB2 G776delinsLC ERBB2 G776delinsVC ERBB2 G776L ERBB2 G778_P780dup ERBB2 G778_S779insLPS ERBB2 H878Y ERBB2 Kinase Domain Mutation ERBB2 L755_T759del ERBB2 L755A ERBB2 L755M ERBB2 L755P ERBB2 L755S ERBB2 L755W ERBB2 L866M ERBB2 M774DELINSWLV ERBB2 Mutation ERBB2 Mutation OR ERBB3 Mutation ERBB2 N857S ERBB2 Overexpression ERBB2 R678Q ERBB2 R896C ERBB2 S310F ERBB2 S310F/Y ERBB2 SERUM LEVELS ERBB2 T798I ERBB2 T798M ERBB2 T862A ERBB2 V773A ERBB2 V777L ERBB2 V842I ERBB2 Y772_A775DUP ERBB3 EXPRESSION ERBB3 G284R ERBB3 Overexpression ERBB3 R103G ERBB3 V104M ERBB3 V855A ERBB4 EXPRESSION ERBB4 Mutation ERBB4 NUCLEAR TRANSLOCATION ERCC1 Expression ERCC1 Underexpression ERCC2 K751Q ERCC5 RS751402 EREG EXPRESSION ERRFI1 E384* ESR1 D538G ESR1 L536Q ESR1 Mutation ESR1 Overexpression ESR1 S463P ESR1 Y537C ESR1 Y537N ESR1 Y537S ETS2 RS461155 ETV4 Overexpression ETV6::ABL1 Fusion ETV6::JAK2 Fusion ETV6::NTRK1 Fusion ETV6::NTRK2 Fusion ETV6::NTRK3 Fusion ETV6::NTRK3 Fusion AND NTRK3 G623R ETV6::RUNX1 Fusion EWSR1::CREB3L1 Fusion EWSR1::DDIT3 Fusion EWSR1::ERG Fusion EWSR1::FLI1 e7::e6 EWSR1::FLI1 Fusion EWSR1::WT1 Fusion EZH2 Activating Mutation EZH2 expression EZH2 Intron 6 Mutation EZH2 Mutation EZH2 Overexpression EZH2 Y646 EZH2 Y646C EZH2 Y646F EZH2 Y646H EZH2 Y646N EZH2 Y646S EZH2 Y646S OR EZH2 Y646F OR EZH2 Y646H OR EZH2 Y646C OR EZH2 Y646N OR EZH2 A692V OR EZH2 A682G FANCC Loss-of-function FBXW7 Loss-of-function FBXW7 Mutation FCGR2A H167R FCGR2B I232T FCGR3A F212V FGF13 CYTOPLASMIC EXPRESSION FGF19 Overexpression FGF2 EXPRESSION FGF3 Amplification FGFR1 Amplification FGFR1 Expression FGFR1 Internal Duplication FGFR1 N546K FGFR1OP2::FGFR1 Fusion FGFR2 Amplification FGFR2 Mutation FGFR2 Mutation OR FGFR2::v Fusion OR FGFR2::? Fusion FGFR2 N550K FGFR2 P253R FGFR2::AHCYL1 Fusion FGFR2::BICC1 Fusion FGFR2::OGA Fusion FGFR2::TACC3 Fusion FGFR2::v Fusion FGFR2::v Fusion OR FGFR2::? Fusion FGFR3 A391E FGFR3 Amplification FGFR3 G370C FGFR3 G380R FGFR3 G697C FGFR3 K650D FGFR3 K650E FGFR3 K650L FGFR3 K650M FGFR3 K650N FGFR3 K650Q FGFR3 K650T FGFR3 Mutation FGFR3 Overexpression FGFR3 R248C FGFR3 S249C FGFR3 V555M FGFR3 Y373C FGFR3::BAIAP2L1 Fusion FGFR3::TACC3 Fusion FGFR3::TACC3 Fusion AND FGFR2::CCDC6 Fusion FIP1L1::PDGFRA Fusion FIP1L1::PDGFRA Fusion AND PDGFRA T674I FLCN c.1285dupC FLT3 Amplification FLT3 D835 FLT3 D835H FLT3 D835H/Y FLT3 D835I FLT3 D835V FLT3 D835Y FLT3 F691L FLT3 ITD FLT3 ITD AND FLT3 D835Y FLT3 Mutation FLT3 Overexpression FLT3 T227M FLT3 TKD MUTATION FLT3 Y842C FNTB RS11623866 FOS Overexpression FOS::v Fusion FOXL2 C134W FOXP1 AMPLIFICATION FOXP1::ABL1 Fusion FOXP3 EXPRESSION FOXR2 Rearrangement FUS::CREB3L2 Fusion FUS::DDIT3 Fusion FUS::ERG Fusion FUS::TFCP2 Fusion FUS::TFCP2 Fusion AND ALK Exon 2-18 Deletion GADD45A rs681673 GAS6 EXPRESSION GATA2 EXPRESSION GNA11 Mutation GNA11 Q209 GNA11 Q209L GNA11 R183C GNAQ Mutation GNAQ Q209 GNAQ Q209P GNAS c.393T>C GNAS R201 GNAS R201H GOLGA4::RAF1 Fusion GOLGA5::JAK2 Fusion GON4L::NTRK1 Fusion GOPC::ROS1 e7::e35 GOPC::ROS1 Fusion GSTP1 Deletion GSTP1 I105V H3-3A G34R H3-3A G34W H3-3A K28M H3-3A MUTATION H3-3B K36M H3C2 K27M HAVCR2 Overexpression HEY1::NCOA2 Fusion HGF EXPRESSION HIF1A 3' UTR Polymorphism HIF1A EXPRESSION HIF1A OVEREXPRESSION HLA-C COPY-NEUTRAL LOSS OF HETEROZYGOSITY HLA-DRA EXPRESSION HMOX1 EXPRESSION HOXB13 G84E HRAS G13D HRAS Mutation HRAS Q61 HSPA5 EXPRESSION HSPB1 EXPRESSION HSPH1 NUCLEAR EXPRESSION HSPH1 T17 DELETION IDH1 Mutation IDH1 R132 IDH1 R132C IDH1 R132C OR IDH1 R132H OR IDH1 R132L OR IDH1 R132G OR IDH1 R132S IDH1 R132H IDH2 Mutation IDH2 Mutation OR IDH1 Mutation IDH2 R140 IDH2 R172 IDH2 R172K IDH2 R172K OR IDH2 R172G OR IDH2 R172W IFNGR1 Loss IGF1R EXPRESSION IGF1R NUCLEAR EXPRESSION IGF1R Overexpression IGF2 Overexpression IGH::CRLF2 Fusion IGH::DUX4 Fusion IGH::EPOR Fusion IGH::IL3 Fusion IGH::MYC Fusion IKZF1 Deletion IKZF1 Loss-of-function IL3 IGH::IL3 IL6 Overexpression JAK1 OVEREXPRESSION JAK1 Q503* JAK1 S703I JAK2 c.1641+1dup JAK2 F694L JAK2 Splice Site (c.1641+2T>G) JAK2 V617F JUN Overexpression KANK1::NTRK2 Fusion KANK4::ALK Fusion KAT6A::CREBBP Fusion Kataegis Positive KDR A1065T KDR D717V KDR R1032Q KDR R961W KIAA1549::BRAF Fusion KIF23 EXPRESSION KIF5B::EGFR Fusion KIF5B::RET Fusion KIT A502_Y503insAY KIT A829P KIT A829P AND ( KIT W557_K558del OR KIT V560_Y578del ) KIT Amplification KIT C809G KIT D579del KIT D816E KIT D816H KIT D816V KIT D820A KIT D820G KIT D820Y KIT Exon 11 Mutation KIT Exon 13 Mutation KIT Exon 14 Mutation KIT Exon 9 Mutation KIT EXPRESSION KIT F506_F508DUP KIT Internal Duplication KIT K484_G487DEL KIT K550_K558del KIT K550_K559DEL KIT K550_W557del KIT K558_V559del KIT K558delinsNP KIT K642E KIT L576P KIT M541L KIT Mutation KIT N822H KIT N822K KIT P551_E554delPMYE KIT rs17084733 KIT RS3733542 KIT S628N KIT T417_D419delinsY KIT T670I KIT V555_V559DEL KIT V559D KIT V560_L576DEL KIT V560D KIT V560DEL KIT V560G KIT V654A KIT W557_K558del KIT Wildtype KIT Y503_F504insAY KIT Y823D KLF5 E419K KLF5 E419Q KLLN PROMOTER METHYLATION KMT2A::v Fusion KMT2C Loss KMT2C Mutation KMT2D Loss-of-function KRAS A11_G12insGA KRAS A146 KRAS A146P KRAS A146T KRAS A146V KRAS Amplification KRAS Exon 2 Mutation KRAS G10_A11insG KRAS G12 KRAS G12 OR KRAS G13 KRAS G12/G13 KRAS G12A KRAS G12C KRAS G12D KRAS G12R KRAS G12S KRAS G12V KRAS G13 KRAS G13D KRAS G13V KRAS Mutation KRAS Q22* KRAS Q61 KRAS Q61H KRAS Q61K KRAS Q61L KRAS Q61R KRAS R164Q KRAS RS61764370 KRAS Wildtype KRT18 UNDEREXPRESSION LEPR UNDEREXPRESSION LMNA::NTRK1 Fusion LMNA::NTRK1 Fusion AND NTRK1 F589L LMNA::NTRK1 Fusion AND NTRK1 G595R LMNA::NTRK1 Fusion AND NTRK1 G595R AND NTRK1 F589L LMNA::NTRK1 Fusion AND NTRK1 G595R AND NTRK1 G667C LMNA::NTRK1 Fusion AND NTRK1 G667C LMNA::NTRK1 Fusion OR TPM3::NTRK1 Fusion LPP::HMGA2 Fusion OR HMGA2::LPP Fusion LRP1B DELETION LRP1B EXON 12-22 DELETION LRP1B Loss-of-function LSM14A::ABL1 Fusion LYN OVEREXPRESSION MACF1::BRAF Fusion MAGEH1 EXPRESSION MAP2K1 C121S MAP2K1 K57N MAP2K1 P124S MAP2K1 Q56_V60del MAP2K1 Q56P MAP2K7 E116K MAPK1 Amplification MAPK1 E322K MDM2 EXPRESSION MDM2 RS34886328 MDM2 SNP309 MECOM rearrangement MEF2D::CSF1R Fusion MEF2D::v Fusion MEN1 FRAMESHIFT TRUNCATION MERTK OVEREXPRESSION MET Amplification MET Amplification AND MET Splice Site (c.3028G>A) MET D1228N MET D1228V MET Exon 14 Skipping Mutation MET Mutation MET Overexpression MET R1004G MET::ATXN7L1 Fusion Methylation signature ST-EPN-ZFTA MGMT Promoter Methylation MGMT RS16906252 MGMT Underexpression MIR218-1 EXPRESSION MIR218-1 UNDEREXPRESSION MKI67 EXPRESSION MLH1 *757L MLH1 A424T MLH1 A681V MLH1 c.790+1G>A MLH1 D667FS MLH1 E13fs MLH1 EXPRESSION MLH1 G606FS*2 MLH1 G65D MLH1 G67R MLH1 I68S MLH1 K618DEL MLH1 M1L MLH1 M490T MLH1 METHYLATION MLH1 N551T MLH1 P138T MLH1 P536FS MLH1 Q149* MLH1 Q426FS MLH1 R100* MLH1 R226* MLH1 R265G MLH1 R687FS MLH1 T117M MLH1 V213FS MLH1 V49A MLH1 V534R MMP2 SERUM LEVELS MMP9 SERUM LEVELS MN1 Rearrangement MN1::BEND2 Fusion MN1::ZFTA Fusion MNX1::ETV6 Fusion MRE11 Frameshift MRE11 Loss MS4A1 Mutation MSH2 E28FS MSH2 E483G MSH2 K172* MSH2 Loss MSH2 Loss OR MLH1 Loss MSH2 R383* MSH2 V273FS MSH6 I891FS MSH6 LOSS MSH6 P138T MSH6 R1242C MSH6 R1242H MSH6 V352I MTAP Deletion MTAP Underexpression MTHFR A222V MTOR A2034V MTOR C1483Y MTOR E1799K MTOR E2014K AND MTOR E2419K MTOR F2108L MTOR H1968Y MTOR M2327I MTOR Mutation MTOR Mutation OR PIK3CA Mutation OR PTEN Mutation OR AKT1 Mutation OR AKT2 Mutation MTOR P2213S MTOR R2152C MTOR S2215Y MTOR T1977K MYB AMPLIFICATION MYB Rearrangement MYB Truncation MYB::QKI Fusion MYBL1 Rearrangement MYC Overexpression MYCL EXPRESSION MYCN Amplification MYD88 L265P MYD88 Overexpression MYOD1 L122R NAPRT Promoter Hypermethylation NCOA3 AMPLIFICATION NCOA3 OVEREXPRESSION NEDD9 EXPRESSION NF1 Loss NF1 Mutation NF1 Mutation OR GNA11 Q209L NF2 c.1396C>T NF2 K159fs NF2 Loss NF2 Y177fs NFE2L2 G31A NFE2L2 Mutation NOT KIT D816V NOTCH1 Amplification NOTCH1 D1642H NOTCH1 Loss-of-function NOTCH1 Mutation NOTCH1 P2514FS NOTCH1 R2327W NOTCH1 S2275FS NOTCH1 V2444FS NPM1 EXON 11 MUTATION NPM1 W288FS NPM1::ALK Fusion NQO1 EXPRESSION NQO1 P187S NRAS G12 NRAS G12/G13 NRAS G12C NRAS G12D NRAS G13D NRAS G13R NRAS Mutation NRAS Q179X NRAS Q61 NRAS Q61H NRAS Q61K NRAS Q61L NRAS Q61R NRF1::BRAF Fusion NRG1 Expression NT5C2 D407A NT5C2 K359Q NT5C2 Mutation NT5C2 R238W NT5C2 R367Q NT5C2 S445F NT5E Overexpression NTRK1 Amplification NTRK1 G595R AND NTRK1 G667S NTRK1 Overexpression NTRK3 Amplification NTRK3 F617L NTRK3 G623R AND EML4::NTRK3 Fusion NTRK3::SCAPER Fusion NUP153::ABL1 Fusion NUP214::ABL1 Fusion NUP98::NSD1 Fusion NUP98::v Fusion OFD1::JAK2 Fusion PALB2 Biallelic Inactivation PALB2 L531FS*30 PALB2 Mutation PAPSS1::BRAF Fusion PARP1 OVEREXPRESSION PAX3::FOXO1 Fusion PAX5 P80R PAX5::JAK2 Fusion PAX7::FOXO1 Fusion PAX8 Expression PAX8::PPARG Fusion PBK NUCLEAR EXPRESSION PBK OVEREXPRESSION PBRM1 Mutation PCM1::JAK2 Fusion PDCD4 EXPRESSION PDE4DIP::NTRK1 Fusion PDGFRA Amplification PDGFRA D842_H845DELDIMH PDGFRA D842_I843delinsVM PDGFRA D842I PDGFRA D842V PDGFRA D842Y PDGFRA Exon 18 Mutation PDGFRA G853D PDGFRA H845Y PDGFRA I843DEL PDGFRA Mutation PDGFRA Overexpression PDGFRA P577S PDGFRA R841K PDGFRA V561A PDGFRA V561D PDGFRB Overexpression PGR Expression PIK3CA Amplification PIK3CA C420R PIK3CA C604R PIK3CA D350G PIK3CA D350N PIK3CA E542K PIK3CA E542K OR PIK3CA E545K OR PIK3CA H1047R PIK3CA E545G PIK3CA E545K PIK3CA E545K OR PIK3CA E545A OR PIK3CA E545G OR PIK3CA E545D PIK3CA E545Q PIK3CA E81K PIK3CA Exon 10 Mutation PIK3CA Exon 21 Mutation PIK3CA Exon 21 Mutation AND PIK3CA Exon 10 Mutation PIK3CA Exon 21 Mutation OR PIK3CA Exon 10 Mutation PIK3CA F930S PIK3CA G1007R PIK3CA G1049R PIK3CA H1047L PIK3CA H1047R PIK3CA H1047R OR PIK3CA H1047L PIK3CA H1047R OR PIK3CA H1047Y OR PIK3CA H1047L PIK3CA I391M PIK3CA K111N PIK3CA K944N PIK3CA K966E PIK3CA L938* PIK3CA Mutation PIK3CA Mutation OR PTEN Mutation OR AKT1 Mutation PIK3CA Mutation OR RB1 Mutation OR ESR1 Mutation PIK3CA N1044K PIK3CA N345K PIK3CA P471L PIK3CA Q546E OR PIK3CA Q546R PIK3CA Q546K PIK3CA R88Q PIK3CA R93W PIK3CA Rare Mutation PIK3CA S158L PIK3CA V955G PIK3CA V955I PIK3CA Wildtype PIK3R1 Mutation PIK3R2 G373R PIK3R2 N561D PIK3R2 Overexpression PIM1 L2V PIM1 NUCLEAR EXPRESSION PIM1 P81S PIM1 S97N PLCG2 MUTATION PML B2 DOMAIN MUTATION PML::RARA Fusion PML::RARA Fusion AND PML A216V PML::RARA Fusion AND PML L218P PMS2 K706FS*19 PMS2 R315* POLD1 C284Y POLD1 E374K POLE Mutation POLE P286R POLE S459F POLE V411L POT1 MUTATION POU5F1 EXPRESSION PPFIBP1::JAK2 Fusion PPFIBP2::BRAF Fusion PPP1R15A RS557806 PPP2R1A P179R PPP2R2A Mutation PRDM1 MUTATION PREX2 R172I PRKAA2 T172 PHOSPHORYLATION PRKCB D427N PROM1 EXPRESSION PRPS1 A190T PRPS1 A87T PRPS1 C77S PRPS1 D139G PRPS1 D183E PRPS1 I72V PRPS1 K176N PRPS1 L191F PRPS1 M115T PRPS1 N144S PRPS1 PRPS1 MUTATION PRPS1 S103I PRPS1 S103N PRPS1 S103T PRPS1 T303S PRPS1 V53A PSMB8 NUCLEAR EXPRESSION PTCH1 LOH PTCH1 Mutation PTEN C136R PTEN Deletion PTEN Expression PTEN Loss PTEN Mutation PTEN R130* PTEN R173C PTEN R233* PTEN V317FS PTP4A3 OVEREXPRESSION PTPN11 Overexpression PTPRB Loss-of-function PTPRD Mutation PTPRD V253I PTPRT Promoter Hypermethylation PTTG1 OVEREXPRESSION QKI::NTRK2 Fusion QKI::RAF1 Fusion RAC1 P29S RAD23B EXPRESSION RAD50 L1237F RAD51B Mutation RAD51D Mutation RAD51D R186* RAD54L Mutation RAF1 Amplification RAF1 R391W RANBP2::ABL1 Fusion RANBP2::ALK Fusion RASA1 Loss-of-function RB1 EXPRESSION RB1 Loss-of-function RB1 M695FS*26 RB1 Mutation RB1 Overexpression RB1 PHOSPHORYLATION RB1 Wildtype AND ( CDKN2A Loss OR CDKN2A Mutation ) RBM15::MRTFA Fusion RCSD1::ABL1 Fusion RCSD1::ABL2 Fusion REL AMPLIFICATION RET C609Y RET C634W RET M918T RET Mutation RET Overexpression RET V804M RFX3::JAK2 Fusion RHOA MUTATION RICTOR Amplification RIT1 Mutation RIT1 OVEREXPRESSION ROBO4 EXPRESSION ROS1 G2032R ROS1 G2032R AND CD74::ROS1 Fusion ROS1 G2032R AND SLC4A4::ROS1 Fusion ROS1 G2032R AND v::ROS1 Fusion ROS1 G2101A AND CD74::ROS1 Fusion ROS1 L2026M AND CD74::ROS1 Fusion ROS1 L2155S AND CD74::ROS1 Fusion RPS6 PHOSPHORYLATION RRM1 Overexpression RRM1 Underexpression RRM2 OVEREXPRESSION RSF1 Amplification RUNX1 A107P RUNX1 D198Y RUNX1 K83E RUNX1 Mutation RUNX1 R135FSX177 RUNX1 T148HFSX9 RUNX1 Y260* RUNX1::RUNX1T1 Fusion SCP2::NTRK1 Fusion SDC4::NRG1 Fusion SDC4::ROS1 Fusion SDHB p.193_196dupSTSC (c.577_588dupAGCACCAGCTGC) SETBP1 Exon 4 Mutation SETBP1 G870S SF3B1 K666N SF3B1 K700E SF3B1 Mutation SFPQ::ABL1 Fusion SGK1 Overexpression SH2B3 RS3184504 SIRT1 Overexpression SLC29A1 Overexpression SLC3A2::NRG1 Fusion SLCO1B1 N130D SLCO1B1 RS4149056 SLFN11 EXPRESSION SMAD2 S276L SMAD4 Deletion SMAD4 Expression SMAD4 LOSS SMAD4 Mutation SMAD4 R361C SMAD4 Underexpression SMARCA2 K755R SMARCA2 R1159Q SMARCA4 INACTIVATING MUTATION SMARCA4 Loss SMARCA4 Mutation SMARCA4 Underexpression SMARCB1 Deletion SMARCB1 Loss SMARCB1 LOSS OF NUCLEAR PROTEIN EXPRESSION SMARCB1 Underexpression SMO D473H SMO L412F SMO Mutation SMU1::JAK2 Fusion SNX2::ABL1 Fusion SNX29::JAK2 Fusion SOX10 Loss SPHK1 OVEREXPRESSION SQSTM1::NTRK1 Fusion SRSF2 MUTATION SRSF2 P95H SRSF2 P95L SS18::SSX1 Fusion SS18::SSX2 Fusion SS18::SSX4 Fusion SSBP2::JAK2 Fusion SSTR5 expression STAG2 MUTATION STAG2 Underexpression STAG3 Underexpression STAT3 SH2 DOMAIN MUTATION STK11 D194E STK11 EXON 1-2 MUTATION STK11 Loss STK11 Mutation STK11 Underexpression STMN1 EXPRESSION STRN::ALK Fusion STRN::NTRK2 Fusion STRN3::JAK2 Fusion SYK OVEREXPRESSION TBK1 Overexpression TBL1XR1::CSF1R Fusion TCF3 TCF3::HLF TCF3::HLF Fusion TCF3::PBX1 Fusion TERF2::JAK2 Fusion TERT Amplification TERT C228T TERT Promoter Mutation TERT RS2736100 TET2 Mutation TFF3 EXPRESSION TFG::ROS1 Fusion TGFA EXPRESSION THBS2 UNDEREXPRESSION TIMP1 Overexpression TLK2 Amplification TMB High TMPRSS2::ERG Fusion TNKS2::PDGFRA Fusion TOP1 Amplification TOP1 EXPRESSION TOP2A EXPRESSION TP53 A161T TP53 A276V TP53 ALTERATION TP53 C124R TP53 C135W TP53 C238Y TP53 C242F TP53 C242S TP53 C242Y TP53 CONSERVED DOMAIN MUT TP53 D259V TP53 D281E TP53 D281N TP53 Deleterious Mutation TP53 DNA Binding Domain Mutation TP53 E224K TP53 E258K TP53 E285K TP53 E286K TP53 E68G TP53 F270S TP53 G154S TP53 G244S TP53 G245D TP53 G245S TP53 G262D TP53 G266E TP53 G266R TP53 G266V TP53 G279E TP53 H115Y TP53 H168Y TP53 H178P TP53 H179R TP53 H179Y TP53 I162F TP53 K139E TP53 L111R TP53 L139N TP53 L252F TP53 L257P TP53 L308M TP53 L323P TP53 L330P TP53 L330R TP53 L344P TP53 Loss TP53 M237I TP53 M246L TP53 Mutation TP53 N239S TP53 Overexpression TP53 P151H TP53 P151S TP53 P152L TP53 P152T TP53 P177F TP53 P177H TP53 P177S TP53 P219H TP53 P250L TP53 P278S TP53 P47S TP53 P72R TP53 P98L TP53 P98S TP53 Q144P TP53 R156H TP53 R156P TP53 R158G TP53 R158H TP53 R158L TP53 R175H TP53 R181C TP53 R181G TP53 R181H TP53 R181P TP53 R213P TP53 R248Q TP53 R248W TP53 R249 TP53 R249S TP53 R273C TP53 R273H TP53 R273L TP53 R280K TP53 R280T TP53 R282L TP53 R282W TP53 R283H TP53 R337P TP53 R342P TP53 R72P TP53 S241F TP53 S241T TP53 T125T TP53 T230S TP53 Truncating Mutation TP53 V157F TP53 V272G TP53 V274F TP53 Wildtype TP53 Y126D TP53 Y126S TP53 Y163H TP53 Y163N TP53 Y220C TP53 Y220H TP53 Y234C TP53 Y234H TP53 Y236S TPM3::NTRK1 Fusion TPR::JAK2 Fusion TPR::NTRK1 Fusion TRIM24::BRAF Fusion TRIM63::NTRK1 Fusion TSC1 Frameshift Truncation TSC1 Loss-of-function TSC1 R1062W TSC2 Q1178* TTF1 AMPLIFICATION TUBB3 EXPRESSION TYMS 5' TANDEM REPEAT TYMS Amplification TYMS Overexpression TYMS RS34743033 TYMS Underexpression U2AF1 MUTATION U2AF1 Q157P/R U2AF1 S34Y/F UGT1A EXPRESSION UGT1A1 UGT1A1*28 UGT1A1 UGT1A1*60 USP25::JAK2 Fusion v::ALK Fusion v::ALK Fusion OR v::ROS1 Fusion v::FGFR1 Fusion v::IRF4 Fusion v::JAK2 Fusion v::MITF Fusion v::NR4A3 Fusion v::NRG1 Fusion v::NTRK1 Fusion v::NTRK2 Fusion v::NTRK3 Fusion v::NUTM1 Fusion v::PDGFRA Fusion v::PDGFRB Fusion v::RET Fusion v::RET Fusion OR RET Mutation v::ROS1 Fusion v::TFCP2 Fusion v::TFE3 Fusion v::TFEB Fusion v::ZNF384 Fusion VCL::NTRK2 Fusion VEGFA Decreased Peri-therapeutic Expression VHL *214C (c.641_642insC) VHL *214C (c.642A>T) VHL *214G (c.640T>G) VHL *214L (c.641G>T) VHL *214W (c.642A>G) VHL 106insR (c.316insGCC) VHL 3'UTR alteration (c.*70C>A) VHL 3'UTR alteration (c.639+10C>G) VHL 3p26.3-25.3 11Mb del VHL A122I (c.364_365GC>AT) VHL A149fs (c.445delG) VHL A149fs (c.449del14-nt) VHL A149S (c.445G>T) VHL A149T (c.445G>A) VHL A56_P59del (c.166_178del) VHL A56fs (c.164_165insA) VHL A56FS (c.164_165insG) VHL A56fs (c.166_167insA) VHL A56fs (c.166dup) VHL c.128-?_250+? VHL c.341-59_341-14del VHL c.竏213竏 ?_463 ?del VHL C162F (c.485G>T) VHL C162fs (c.483del) VHL C162R (c.484T>C) VHL C162W (c.486C>G) VHL C162Y (c.485G>A) VHL C77_N78insL (c.230_231insTCT) VHL C77fs (c.228dup) VHL C77fs (c.230del) VHL D121_A122del (c.361_366del) VHL D121G (c.362A>G) VHL D126FS (c.375_376insC) VHL D143fs (c.430delG) VHL D197FS (c.589delG) VHL D92G (c.275A>G) VHL Deletion VHL E160fs (c.477del) VHL E160fs (c.479_480delAG) VHL E186* (c.556G>T) VHL E186K (c.556G>A) VHL E189fs (c.565del) VHL E46* (c.136G>T) VHL E52K (c.154G>A) VHL E55* (c.163G>T) VHL E55= (c.165G>A) VHL E55FS (c.163_164delGA) VHL E55fs (c.163delG) VHL E55RfsTer11 (c.163delG) VHL E70* (c.208G>T) VHL E70K (c.208G>A) VHL E94* (c.280G>T) VHL E94FS (c.279delC) VHL Exon 1 Deletion VHL Exon 1-2 Deletion VHL Exon 1-3 Deletion VHL Exon 2 Deletion VHL EXON 2-3 DELETION VHL Exon 3 Deletion VHL F119L (c.357C>G) VHL F136C (c.407T>G) VHL F136S (c.407T>C) VHL F148* (c.443_455delinsA) VHL F76del (c.227_229del) VHL F76fs (c.223_224insT) VHL F76S (c.227T>C) VHL F91* (c.272_273delinsAA) VHL F91L (c.273C>G) VHL G104= (c.312C>G) VHL G104A (c.311G>C) VHL G104V (c.311G>T) VHL G114C (c.340G>T) VHL G114dup (c.342dupGGT) VHL G114R (c.340G>C) VHL G114S (c.340G>A) VHL G114Vfs*45 (c.339delA) VHL G123fs (c.369_375delGACACAC) VHL G144* (c.430G>T) VHL G144E (c.431G>A) VHL G144fs (c.429_439del) VHL G144fs (c.432insG) VHL G93_Y98del (c.275_292del) VHL G93C (c.277G>T) VHL G93D (c.278G>A) VHL G93R (c.277G>C) VHL G93S (c.277G>A) VHL G93V (c.278G>T) VHL H115fs (c.344del) VHL H115P (c.344A>C) VHL H115Q (c.345C>A) VHL H115Q (c.345C>G) VHL H115R (c.344A>G) VHL H115Y (c.343C>T) VHL H125fs (c.374insA) VHL H191FS (c.571delC) VHL I151F (c.451A>T) VHL I151M (c.453C>G) VHL I151T (c.452T>C) VHL I180V (c.538A>G) VHL Intronic deletion (c.341-13delCGTTTCCAACAATTTCTCGGTGT) VHL K159fs (c.473dup) VHL K159fs (c.474_476delGAAinsC) VHL K159fs (c.477_478insCA) VHL K196* (c.586A>T) VHL K196fs (c.584_585delAG) VHL L101G (c.301_302delinsGG) VHL L116V (c.346C>G) VHL L118fs (c.352_353insA) VHL L118P (c.353T>C) VHL L128F (c.382C>T) VHL L128R (c.383T>G) VHL L129fs (c.384delT) VHL L129P (c.386T>C) VHL L129Q (c.386insAGA) VHL L135* (c.404T>A) VHL L135fs (c.404del) VHL L140fs (c.417_418delTC) VHL L153fs (c.457delC) VHL L153P (c.458T>C) VHL L158fs (c.471dupT) VHL L158P (c.473T>C) VHL L158V (c.472C>G) VHL L163H (c.488T>A) VHL L169P (c.506T>C) VHL L178P (c.532C>T) VHL L178P (c.533T>C) VHL L178Q (c.533T>A) VHL L178R (c.533T>G) VHL L184P (c.551T>C) VHL L184R (c.551T>G) VHL L188fs (c.562delC) VHL L188P (c.563T>C) VHL L188Q (c.563T>A) VHL L188R (c.563T>G) VHL L188V (c.562C>G) VHL L198Q (c.593T>A) VHL L85P (c.254T>C) VHL L89P (c.266T>C) VHL Loss VHL Loss-of-function VHL M1? (c.1-1_20del21) VHL M1? (c.3G>A) VHL M1FS (c.1_17del17) VHL M54fs (c.161dup) VHL M54IFS (c.162_166delGGAGG) VHL Mutation VHL N131fs (c.390_391del) VHL N131K (c.393C>A) VHL N131S (c.392A>G) VHL N131T (c.392A>C) VHL N150fs (c.445_458del) VHL N150fs (c.447del) VHL N150fs (c.448delA) VHL N150fs (c.449del) VHL N150S (c.449A>G) VHL N78H (c.232A>C) VHL N78I (c.233A>T) VHL N78S (c.233A>G) VHL N78T (c.233A>C) VHL N7D (c.19A>G) VHL Null (Large deletion) VHL Null (Partial deletion of Exons 2 & 3) VHL P102fs (c.305delC) VHL P103FS (c.309_310delTG) VHL P138R (c.413C>G) VHL P138T (c.412C>A) VHL P146fs (c.437del) VHL P154= (c.462A>C) VHL P154fs (c.462delA) VHL P154L (c.461C>T) VHL P25L (c.74C>T) VHL P40fs (c.118ins) VHL P59fs (c.173_174insC) VHL P59fs (c.176delC) VHL P61FS (c.182_185delCCGT) VHL P61fs (c.183insC) VHL P71fs (c.211insT) VHL P81S (c.241C>T) VHL P81S (c.241C>T) and L188V (c.562C>G) VHL P86A (c.256C>G) VHL P86fs (c.254_255insC) VHL P86L (c.257C>T) VHL P86R (c.257C>G) VHL P86S (c.256C>T) VHL Q132* (c.394C>T) VHL Q132P (c.395A>C) VHL Q145* (c.433C>T) VHL Q164* (c.490C>T) VHL Q164L (c.491A>T) VHL Q164R (c.491A>G) VHL Q195* (c.583C>T) VHL Q73* (c.217C>T) VHL Q73fs (c.214insGCCC) VHL Q73FS (c.217delC) VHL Q96_P97delinsH (c.288_290del) VHL Q96* (c.286C>T) VHL R107G (c.319C>G) VHL R107H (c.320G>A) VHL R107P (c.320G>C) VHL R108dup (c.322_324dup) VHL R113* (c.337C>T) VHL R113FS (c.337delC) VHL R120fs (c.358_359insAC) VHL R120G (c.358A>G) VHL R161* (c.481C>T) VHL R161= (c.481C>A) VHL R161G (c.481C>G) VHL R161P (c.482G>C) VHL R161Q (c.482G>A) VHL R167fs (c.502insTTGTCCGT) VHL R167L (c.500G>T) VHL R167P (c.500G>C) VHL R167Q (c.500G>A) VHL R167W (c.499C>T) VHL R176fs (c.526del) VHL R177* (c.529A>T) VHL R177fs (c.528del) VHL R177ins (c.531insCTGAGAGTAAAGCCTGAA) VHL R200W (c.598C>T) VHL R60FS (c.179delG) VHL R64P (c.191G>C) VHL R69fs (c.204insG) VHL R79_S80del (c.236_241delGCAGTC) VHL R79P (c.236G>C) VHL R82_V84del (c.243_251del) VHL R82_V84del (c.244_252del) VHL R82P (c.245G>C) VHL Rearrangement VHL S111C (c.330_331delinsTT) VHL S111C (c.331A>T) VHL S111FS (c.331delA) VHL S111N (c.332G>A) VHL S111R (c.333C>G) VHL S183* (c.548C>A) VHL S65* (c.194C>A) VHL S65A (c.193T>G) VHL S65FS (c.194delC) VHL S65L (c.194C>T) VHL S65P (c.193T>C) VHL S65W (c.194C>G) VHL S68P (c.202T>C) VHL S68W (c.203C>G) VHL S72fs (c.214del) VHL S72P (c.214T>C) VHL S80fs (c.239del) VHL S80I (c.239G>T) VHL S80N (c.239G>A) VHL S80R (c.238A>C) VHL S80R (c.240T>G) VHL Splice Region (c.340+5G>C) VHL Splice Region (c.463+8C>T) VHL Splice Site (c.340+1G>A) VHL Splice Site (c.341-2A>C) VHL Splice Site (c.463+1G>C) VHL Splice Site (c.463+2T>C) VHL Splice Site (c.464-1G>A) VHL Splice Site (c.464-1G>C) VHL Splice Site (c.464-1G>T) VHL Splice Site (c.464-2A>G) VHL Splice Site (c.464-2A>T) VHL T105P (c.313A>C) VHL T133fs (c.397del) VHL T152fs (c.455insA) VHL T157fs (c.472ins) VHL T157I (c.470C>T) VHL T202fs (c.606insA) VHL V130L (c.388G>C) VHL V155E (c.464T>A) VHL V155G (c.464T>G) VHL V155L (c.463G>C) VHL V166A (c.497T>C) VHL V166D (c.497T>A) VHL V166F (c.496G>T) VHL V170D (c.509T>A) VHL V170F (c.508G>T) VHL V170G (c.509T>G) VHL V181fs (c.540_543del) VHL V194fs (c.581_582del) VHL V62Cfs*5 (c.180del) VHL V66del (c.197_220del) VHL V66Gfs*89 (c.197_209del) VHL V74G (c.221T>G) VHL V84L (c.250G>T) VHL V84M (c.250G>A) VHL V87fs (c.255_256insC) VHL V87fs (c.259_260insA) VHL W117C (c.351G>T) VHL W117fs (c.349dup) VHL W8* (c.24G>A) VHL W88* (c.263G>A) VHL W88* (c.264G>A) VHL W88fs (c.261dup) VHL W88FS (c.263_265delGGCinsTT) VHL W88R (c.262T>A) VHL W88R (c.262T>C) VHL W88S (c.263G>C) VHL Y112* (c.336C>A) VHL Y112H (c.334T>C) VHL Y156* (c.468T>G) VHL Y156C (c.467A>G) VHL Y156D (c.466T>G) VHL Y156N (c.466T>A) VHL Y175* (c.525C>A) VHL Y175* (c.525C>G) VHL Y175* (c.525delC) VHL Y175C (c.524A>G) VHL Y175D (c.523T>G) VHL Y175N (c.523T>A) VHL Y185* (c.555C>G) VHL Y98C (c.293A>G) VHL Y98FS (c.291_310del20) VHL Y98FS (c.291delC) VHL Y98H (c.292T>C) VPS37A Underexpression WEE1 RS3910384 WT1 Exon 7 Mutation WT1 Exon 9 Mutation WWTR1::CAMTA1 Fusion XRCC1 Q399R XRCC1 R194W YAP1::FAM118B Fusion YAP1::MAMLD1 Fusion YAP1::TFE3 Fusion YAP1::v Fusion YWHAE YWHAE::NUTM2 YWHAE::NUTM2A Fusion OR YWHAE::NUTM2B Fusion OR YWHAE::NUTM2E Fusion ZEB1 Expression ZFTA::MAML2 Fusion ZFTA::NCOA1 Fusion ZFTA::NCOA2 Fusion ZFTA::RELA Fusion ZFTA::v Fusion ZKSCAN1::BRAF Fusion ZMIZ1::ABL1 Fusion ZMYM2::FGFR1 Fusion ZMYM2::FGFR1 Fusion OR BCR::FGFR1 Fusion OR CEP43::FGFR1 Fusion OR TRIM24::FGFR1 Fusion OR FGFR1 Translocation ZNF274::JAK2 Fusion ZNF430::JAK2 Fusion
